BIOPEP-UWM: Report

ID 7877
Name peptide derived from bovine beta-casein (170-176)
sequence
VLPVPQK
Function:
Peptide obtained by hydrolysis of bovine b-casein (Eurial, Rennes, France) by use of trypsin. Inhibition activity against Lox-catalyzed linoleate oxidation (initial rate kinetics) amounted to 10%.
 
Number of residues
7
Activity code
lox
Activity :
lipoxygenase inhibitor
Chemical mass 779.9643 Monoisotopic mass 779.4890
EC50 :
0.00 µM


Bibliographic data:
Authors
Rival S.G., Fornaroli S., Boeriu C.G., Wichers H.J.
Title
Caseins and casein hydrolysates. 1. Lipoxygenase inhibitory properties. J. Agric. Food Chem., 49 (2001), 287–294.
Year Source
2001 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CCCCN)C(=O)O

InChI=1S/C37H65N9O9/c1-20(2)19-25(43-34(51)29(40)21(3)4)35(52)45-17-9-13-27(45)33(50)44-30(22(5)6)36(53)46-18-10-12-26(46)32(49)41-23(14-15-28(39)47)31(48)42-24(37(54)55)11-7-8-16-38/h20-27,29-30H,7-19,38,40H2,1-6H3,(H2,39,47)(H,41,49)(H,42,48)(H,43,51)(H,44,50)(H,54,55)/t23-,24-,25-,26-,27-,29-,30-/m0/s1

InChIKey=NKNBSECGZPVWGH-YYLRFZLMSA-N


Predicted ligand of Thrombin (EC 3.4.21.5) (MEROPS ID: S01.217) (PDB code: 2BVR) according to the BIOPEP-UWM Virtual database (ID 219)

Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10243); the MBPDB database;
Antibacterial peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10242)
Peptide stimulating osteoblast differentiation according to the BIOPEP-UWM database of bioactive peptides (ID 10244); the MBPDB database
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 10246); the MBPDB database
Peptide stimulating fibroblast migration and exhibiting antiaging effect according to the BIOPEP-UWM database of bioactive peptides (ID 10247)
Anti-apoptotic peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10245)


Database reference:
AHTPDB: ID 4343

BioPepDB: ID biopep01419

BIOPEP-UWM database of bioactive peptides: ID 10242; 10243; 10244; 10245; 10246; 10247

BIOPEP-UWM Virtual database: ID 219

DFBP: ID DFBPANOX0279; DFBPANTH0161; DFBPDPIV0189

EROP-Moscow: ID E14748

FeptideDB: ID 7877

J-Global: ID 200907043295090643

MBPDB: peptide VLPVPQK

Nikkaji: ID J1.075.676F

PubChem: CID 14389263

SATPdb: ID satpdb27718