BIOPEP-UWM: Report

ID 8090
Name Antioxidative peptide derived from sardine muscle
sequence
MY

Function:
This peptide stimulates expression of the antioxidant defense protein HO-1 in a concentration-depended manner.
 
Number of residues
2
Activity code
ao
Activity :
antioxidative
Chemical mass 312.3849 Monoisotopic mass 312.1139
EC50 :
0.00 µM



Bibliographic data:
Authors
Erdmann K., Grosser N., Schipporeit K., Schröder H.
Title
The ACE inhibitory dipeptide Met-Tyr diminishes free radical formation in human endothelial cells via induction of heme oxygenase-1 and ferritin. Journal of Nutrition, 136 (2006), 2148-2152.
Year Source
2006 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCSC)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O

InChI=1S/C14H20N2O4S/c1-21-7-6-11(15)13(18)16-12(14(19)20)8-9-2-4-10(17)5-3-9/h2-5,11-12,17H,6-8,15H2,1H3,(H,16,18)(H,19,20)/t11-,12-/m0/s1

InChIKey=PESQCPHRXOFIPX-RYUDHWBXSA-N


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8838)
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 3388); the EROP-Moscow database
Inhibitor of tripeptidyl peptidase II (EC 3.4.14.10) (MEROPS ID: S08.090) according to the BIOPEP-UWM database of bioactive peptides; the BRENDA database



Database reference:
AHTPDB: ID 1095, 1357, 2792, 3997, 4726, 5166, 5615, 6173, 6372

BIOPEP-UWM database of bioactive peptides: ID 3388; 8838

BRENDA: Ligand Met-Tyr-OH

CAS: Registry No 13589-04-3

ChEBI: ID 73615

ChemSpider: ID 5373137

EPA CompTox: ID DTXSID10874592

EROP-Moscow: ID E01332

J-GLOBAL: ID 200907099510465373

Metabolomics Workbench: ID 78914

Nikkaji: ID J81.650G

PubChem: CID 7009558

SATPdb: ID satpdb13539

SureChEMBL: ID SCHEMBL7609995

Wikidata: ID Q27141932