BIOPEP-UWM: Report

ID 8138
Name Antioxidative peptide derived from algae protein waste (Chlorella vulgaris)
sequence
VECYGPNRPQF
Function:
The peptide revealed much better antioxidant activity toward peroxyl radicals and LDL than those of Trolox*. *Trolox - 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid, a water-soluble derivative of vitamin E.
 
Number of residues
11
Activity code
ao
Activity :
antioxidative
Chemical mass 1309.4473 Monoisotopic mass 1308.5902
EC50 :
0.00 µM


Bibliographic data:
Authors
Sheih I.-C., Fang T.J., Wu T.-K., Lin P.-H.
Title
Anticancer and antioxidant activities of the peptide fraction from algae protein waste. J. Agric. Food Chem., 58, 1202-1206, 2010
Year Source
2010 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CS)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)O

InChI=1S/C58H84N16O17S/c1-30(2)47(61)55(88)67-35(19-21-46(79)80)50(83)72-40(29-92)52(85)69-37(25-32-14-16-33(75)17-15-32)48(81)65-28-45(78)73-23-7-12-41(73)53(86)70-38(27-44(60)77)51(84)68-36(11-6-22-64-58(62)63)56(89)74-24-8-13-42(74)54(87)66-34(18-20-43(59)76)49(82)71-39(57(90)91)26-31-9-4-3-5-10-31/h3-5,9-10,14-17,30,34-42,47,75,92H,6-8,11-13,18-29,61H2,1-2H3,(H2,59,76)(H2,60,77)(H,65,81)(H,66,87)(H,67,88)(H,68,84)(H,69,85)(H,70,86)(H,71,82)(H,72,83)(H,79,80)(H,90,91)(H4,62,63,64)/t34-,35-,36-,37-,38-,39-,40-,41-,42-,47-/m0/s1

InChIKey: MKKYPTUWZLUJKL-VGGCNYALSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001



Peptide obtained by hydrolysis of algae protein waste by use of pepsin. Algae protein waste is a by-product during production of algae essence from Chlorella vulgaris.


Anticancer peptide according to the BIOPEP-UWM database of bioactive peptides (ID 8137)
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database, BIOPEP-UWM database of bioactive peptides (ID 8997)


Database reference:
AHTPDB: ID 1035, 2966

BioPepDB: ID biopep01348

BIOPEP-UWM database of bioactive peptides: ID 8137, 8997

EROP-Moscow: ID E10346

SATPdb: ID satpdb12643