BIOPEP-UWM: Report

ID 8169
Name ACE inhibitor
sequence
GPVRGPFPII
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
10
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 1052.2661 Monoisotopic mass 1051.6160
IC50 :
0.00 µM


Bibliographic data:
Authors
Hernandez-Ledesma B., Amigo L., Ramos M., Recio I.
Title
Angiotensin converting enzyme inhibitory activity in commercial fermented products. Formation of peptides under simulated gastrointestinal digestion. J. Agric. Food Chem. 52, 1504–1510, 2004
Year Source
2004 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)O

InChI=1S/C51H81N13O11/c1-7-30(5)41(48(72)61-42(50(74)75)31(6)8-2)60-46(70)37-21-15-25-64(37)49(73)34(26-32-16-10-9-11-17-32)58-44(68)35-19-14-24-63(35)39(66)28-56-43(67)33(18-12-22-55-51(53)54)57-47(71)40(29(3)4)59-45(69)36-20-13-23-62(36)38(65)27-52/h9-11,16-17,29-31,33-37,40-42H,7-8,12-15,18-28,52H2,1-6H3,(H,56,67)(H,57,71)(H,58,68)(H,59,69)(H,60,70)(H,61,72)(H,74,75)(H4,53,54,55)/t30-,31-,33-,34-,35-,36-,37-,40-,41-,42-/m0/s1

InChIKey=UMQRNERFPHYGAM-SNDBGJAESA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001

Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 8286); the DFBP database


Database reference:
AHTPDB: ID 6756

BIOPEP-UWM database of bioactive peptides: ID 8286

DFBP: ID DFBPACEI0861; DFBPANOX0344; DFBPMUFU0185

Peptipedia: ID 291

SATPdb: ID satpdb22162