BIOPEP-UWM: Report

ID 8179
Name Peptide derived from ovine alpha S2-casein (165–170)
sequence
LKKISQ

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
6
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 715.8792 Monoisotopic mass 715.4578
IC50 :
2.60 µM



Bibliographic data:
Authors
Lopez-Exposito I., Quiros A., Amigo L., Recio I.
Title
Casein hydrolysates as a source of antimicrobial, antioxidant and antihypertensive peptides. Lait, 87 (2007), 241–249.
Year Source
2007 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@]([H])(C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCC(N)=O)C(O)=O)[C@@]([H])(C)CC

InChI=1S/C32H61N9O9/c1-5-19(4)26(31(48)40-24(17-42)30(47)39-23(32(49)50)12-13-25(36)43)41-29(46)22(11-7-9-15-34)38-28(45)21(10-6-8-14-33)37-27(44)20(35)16-18(2)3/h18-24,26,42H,5-17,33-35H2,1-4H3,(H2,36,43)(H,37,44)(H,38,45)(H,39,47)(H,40,48)(H,41,46)(H,49,50)/t19-,20-,21-,22-,23-,24-,26-/m0/s1

InChIKey=BTDBLUHFSDYXHC-HXDUVXNTSA-N


Peptide obtained by hydrolysis of ovine alpha S2-casein by use of porcine pepsin A.


Antibacterial peptide according to the BIOPEP-UWM database of bioactive peptides (ID 3961); the EROP-Moscow database; the MBPDB database



Database reference:
AHTPDB: ID 4312, 5690

BioPepDB: biopep00802

BIOPEP-UWM database of bioactive peptides: ID 3961

ChemSpider: ID 17259297

EPA DSSTox: ID DTXSID60582857

EROP-Moscow: ID E23859

FeptideDB: ID 3971; 8179

MBPDB: Peptide LKKISQ

PubChem: CID 16101417

SATPdb: ID satpdb26574