BIOPEP-UWM: Report

ID 8304
Name Dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
sequence
IPA
Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
3
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 299.3650 Monoisotopic mass 299.1839
EC50 :
49.00 µM


Bibliographic data:
Authors
Tulipano G., Sibilia V., Caroli A. M., Cocchi D.
Title
Whey proteins as source of dipeptidyl dipeptidase IV (dipeptidyl peptidase-4) inhibitors. Peptides, 32, 835-838, 2011
Year Source
2011 Journal


Additional information:
BIOPEP database of bioactive peptides


SMILES: N[C@H](C(=O)N1[C@H](C(=O)N[C@H](C(=O)O)C)CCC1)[C@H](CC)C

InChI=1S/C14H25N3O4/c1-4-8(2)11(15)13(19)17-7-5-6-10(17)12(18)16-9(3)14(20)21/h8-11H,4-7,15H2,1-3H3,(H,16,18)(H,20,21)/t8-,9-,10-,11-/m0/s1

InChIKey: IITVUURPOYGCTD-NAKRPEOUSA-N


Information concerning Dipeptidyl Peptidase IV (synonym: Dipeptidyl Aminopeptidase IV) (EC 3.4.14.5) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: S09.003

Another reference concerning peptide: Lacroix I. M. E., Li-Chan E. C. Y., 2012, Evaluation of the potential of dietary proteins as precursors of dipeptidyl peptidase (DPP)-IV inhibitors by an in silico approach. J. Funct. Foods, 4, 403-422

Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 3507); the MBPDB database
Antihypertensive peptide according to the EROP-Moscow database


Database reference:
AHTPDB: ID 1146, 1300, 1588, 1661, 1740, 2261,2579, 3772, 3953, 4160, 4377, 4747, 4969, 4984, 5218, 5562, 5947, 6426, 6864,

BioPepDB: ID biopep00555

BIOPEP-UWM database of bioactive peptides: ID 3507

ChemSpider: ID 8215957

EROP-Moscow: ID E14685

FeptideDB: ID 3507; 8304

MBPDB: Peptide IPA

PlantPepDB: ID PPepDB_86

PubChem: CID 10040393

SATPdb: ID satpdb23815