BIOPEP-UWM: Report

ID 8323
Name Glucose uptake stimulating peptide
sequence
IL

Function:
Glucose uptake stimulating
 
Number of residues
2
Activity code
sti
Activity :
stimulating
Chemical mass 244.3296 Monoisotopic mass 244.1781
EC50 :
0.00 µM



Bibliographic data:
Authors
Morifuji M., Koga J., Kawanaka K., Higuchi M.
Title
Branched-chain amino acid-containing dipeptides, identified from whey protein hydrolysates, stimulate glucose uptake in L6 myotubes and isolated skeletal muscles. J. Nutr. Sci. Vitaminol., 55, 81-86, 2009
Year Source
2009 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@H](C(=O)N[C@H](C(=O)O)CC(C)C)[C@H](CC)C

InChI=1S/C12H24N2O3/c1-5-8(4)10(13)11(15)14-9(12(16)17)6-7(2)3/h7-10H,5-6,13H2,1-4H3,(H,14,15)(H,16,17)/t8-,9-,10-/m0/s1

InChIKey: JWBXCSQZLLIOCI-GUBZILKMSA-N


Another reference concerning glucose uptake-stimulating activity:

Morato P. N., Lollo P. C. B., Moura C. S., Batista T. M., Carneiro E. M., Amaya-Farfan J., 2013, A dipeptide and an amino acid present in whey protein hydrolysate increase translocation of GLUT-4 to the plasma membrane in Wistar rats. Food Chem., 139, 853-859


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8802)
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 9079)
Antinociceptive neuropeptide according to the ChEMBL database; the PubChem database
Inhibitor of citrulline uptake in yeasts according to the ChEMBL database; the PubChem database


Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids; ChEMBL database; PubChem database




Database reference:
AHTPDB: ID 1438; 3860; 5410

BindingDB: ID 50282190

BioPepDB: ID biopep00542

BIOPEP-UWM database of bioactive peptides: ID 8802; 9079

BIOPEP-UWM database of sensory peptides and amino acids: ID 194

BRENDA: Ligand Ile-Ieu

ChEBI: ID 74072

ChEMBL: ID CHEMBL48832

ChemSpider: ID 5382050

EPA CompTox: ID DTXSID00427071

EPA DSSTox: ID DTXCID40377905

EROP-Moscow: ID E10605

J-GLOBAL: ID 200907038945135805

Metabolights: ID MTBLC74072

Nikkaji: ID J1.013.425K

PubChem: ID 7019083

SATPdb: ID satpdb25152

SureChEMBL: ID SCHEMBL3010040

ZINC: ID ZINC02556613