BIOPEP-UWM: Report

ID 8359
Name ACE inhibitor from bovine alphas1-CN (143-149)
sequence
AYFYPEL
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
7
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 901.9980 Monoisotopic mass 901.4207
IC50 :
6.58 µM


Bibliographic data:
Authors
Stuknyte M., Cattaneo S., Masotti F., De Noni I.
Title
Occurrence and fate of ACE-inhibitor peptides in cheeses and in their digestates following in vitro static gastrointestinal digestion. Food Chemistry, 168, 27-33.
Year Source
2015 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](C)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H](CC3=CC=C(C=C3)O)C(=O)N4[C@@H](CCC4)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)O

InChI=1S/C46H59N7O12/c1-26(2)22-37(46(64)65)52-41(59)33(19-20-39(56)57)48-44(62)38-10-7-21-53(38)45(63)36(25-30-13-17-32(55)18-14-30)51-43(61)35(23-28-8-5-4-6-9-28)50-42(60)34(49-40(58)27(3)47)24-29-11-15-31(54)16-12-29/h4-6,8-9,11-18,26-27,33-38,54-55H,7,10,19-25,47H2,1-3H3,(H,48,62)(H,49,58)(H,50,60)(H,51,61)(H,52,59)(H,56,57)(H,64,65)/t27-,33-,34-,35-,36-,37-,38-/m0/s1

InChIKey=OVPWZIOKYPAYJR-XZUOCMGYSA-N


Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9175); the MBPDB database
Peptide stimulating mucin secretion according to the MBPDB database


Database reference:
AHTPDB: ID 1719, 1758, 2348, 2612, 2951, 3680, 4147, 5032

BioPepDB: ID biopep00104

BIOPEP-UWM database of bioactive peptides: ID 9175

ChemSpider: ID 17259300

EROP-Moscow: ID E23678

FeptideDB: ID 8359

J-GLOBAL: ID 201507077421025320

MBPDB: Peptide AYFYPEL

Nikkaji: ID J3.347.045B

PubChem: CID 16101420

SATPdb: ID satpdb24128