BIOPEP-UWM: Report

ID 8391
Name ACE inhibitor from egg white
sequence
YAEERYPIL
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
9
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 1153.2806 Monoisotopic mass 1152.5796
IC50 :
0.00 µM


Bibliographic data:
Authors
Babij K., Dąbrowska A., Szołtysik M., Pokora M., Zambrowicz A., Chrzanowska J.
Title
Int. J. Pept. Res. Ther., 20, 483–491, 2014
Year Source
2014 Journal


Additional information:
Full title of reference paper: The Evaluation of Dipeptidyl Peptidase (DPP)-IV, alpha-Glucosidase and Angiotensin Converting Enzyme (ACE) Inhibitory Activities of Whey Proteins Hydrolyzed with Serine Protease Isolated from Asian Pumpkin (Cucurbita ficifolia). Int. J. Pept. Res. Ther., 20, 483–491, 2014 (authors: Babij K., Dąbrowska A., Szołtysik M., Pokora M., Zambrowicz A., Chrzanowska J.).



BIOPEP database of bioactive peptides


SMILES: [H][C@](N)(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])(CC(C)C)C(O)=O

InChI=1S/C54H80N12O16/c1-6-29(4)44(51(79)64-40(53(81)82)25-28(2)3)65-50(78)41-10-8-24-66(41)52(80)39(27-32-13-17-34(68)18-14-32)63-47(75)36(9-7-23-58-54(56)57)61-49(77)38(20-22-43(71)72)62-48(76)37(19-21-42(69)70)60-45(73)30(5)59-46(74)35(55)26-31-11-15-33(67)16-12-31/h11-18,28-30,35-41,44,67-68H,6-10,19-27,55H2,1-5H3,(H,59,74)(H,60,73)(H,61,77)(H,62,76)(H,63,75)(H,64,79)(H,65,78)(H,69,70)(H,71,72)(H,81,82)(H4,56,57,58)/t29-,30-,35-,36-,37-,38-,39-,40-,41-,44-/m0/s1

INChIKey: KJFSHDGRGPPBOK-KLCRLARCSA-N

Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Database reference:
AHTPDB: ID 1346, 1744, 1751, 1966, 2338, 4197, 4463, 5039, 6650

SATPdb: ID satpdb20004