BIOPEP-UWM: Report

ID 8504
Name Dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
sequence
WP
Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
2
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 301.3396 Monoisotopic mass 301.1422
IC50 :
4530.00 µM


Bibliographic data:
Authors
Hatanaka T., Inoue Y., Arima J., Kumagai Y., Usuki H., Kawakami K., Kimura M., Mukaihara T.
Title
Production of dipeptidyl peptidase IV inhibitory peptides from defatted rice bran. Food Chem., 134, 797-802, 2012
Year Source
2012 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)N1[C@@]([H])(CCC1)C(=O)O

InChI=1S/C16H19N3O3/c17-12(15(20)19-7-3-6-14(19)16(21)22)8-10-9-18-13-5-2-1-4-11(10)13/h1-2,4-5,9,12,14,18H,3,6-8,17H2,(H,21,22)/t12-,14-/m0/s1

InChIKey=DXYQIGZZWYBXSD-JSGCOSHPSA-N


First reference containing DPPIV inhibitory activity:
Yamada M., Okagaki C., Higashijima T., Tanaka S., Ohnuki T., Sugita T., 1998, A potent dipeptide inhibitor of dipeptidyl peptidase IV. Bioorg. Med. Chem. Lett., 8, 1537-1540


Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database, the BIOPEP-UWM database of bioactive peptides; the EROP-Moscow database

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 341)


Database reference:
AHTPDB: ID 2795

BIOPEP-UWM database of bioactive peptides: ID 8504

BIOPEP-UWM database of sensory peptides and amino acids: ID 341

BRENDA: Ligand Trp-Pro

CAS: Registry No 38136-75-3

ChEBI: ID 141449

ChEMBL: ID CHEMBL417328

ChemSpider: ID 8015051

ECHA: ID 917-507-6

EPA CompTox: ID DTXSID801314501

EROP-Moscow: ID E10414

J-GLOBAL: ID 201207099571789800

Nikkaji: ID J3.055.861H

PubChem: CID 9839333

SATPdb: ID satpdb19398

SureChEMBL: ID SCHEMBL9852012

UniChem: ID 256427

Wikidata: ID Q106026422

ZINC: ID ZINC000002572698