BIOPEP-UWM: Report

ID 8506
Name dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
sequence
FP
Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
2
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 262.3036 Monoisotopic mass 262.1313
IC50 :
363.00 µM


Bibliographic data:
Authors
Hatanaka T., Inoue Y., Arima J., Kumagai Y., Usuki H., Kawakami K., Kimura M., Mukaihara T.
Title
Production of dipeptidyl peptidase IV inhibitory peptides from defated rice bran. Food Chem., 134, 797-802
Year Source
2012 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC1=CC=C(C=C1))C(=O)N1[C@@]([H])(CCC1)C(=O)O

InChI=1S/C14H18N2O3/c15-11(9-10-5-2-1-3-6-10)13(17)16-8-4-7-12(16)14(18)19/h1-3,5-6,11-12H,4,7-9,15H2,(H,18,19)/t11-,12-/m0/s1

InChIKey=WEQJQNWXCSUVMA-RYUDHWBXSA-N

Information concerning Dipeptidyl Peptidase IV (synonym: Dipeptidyl Aminopeptidase IV) (EC 3.4.14.5) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: S09.003


Peptide found in amaranth (Amarantus hypochondriacus) proteins:

Barba de la Rosa A. P., Barba Montoya A., Martínez-Cuevas P., Hernández-Ledesma B., León-Galván M. F., De León-Rodríguez A., González C., 2010, Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: antihypertensive role of amaranth peptides. Nitric Oxide, 23, 106-111


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 3502); the EROP-Moscow database
Antifungal peptide according to the EROP-Moscow database

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 45); EROP-Moscow database


Database reference:
AHTPDB: ID 1135; 1334; 1366; 1664; 1743; 2580; 3181; 3204; 3396; 3556; 3596; 3878; 3909; 4071; 4161; 4728; 4949; 5147; 5417; 5565; 5585; 5702; 5948; 6421; 6865

BIOPEP-UWM database of bioactive peptides: ID 3502

BIOPEP-UWM database of sensory peptides and amino acids; ID 45

BRENDA: Ligand Phe-Pro

CAS: ID 7669-65-0

ChEBI: ID 74750

ChEMBL: ID CHEMBL1807686

ChemSpider ID: 5383590

EROP-Moscow: ID E04808; E01602; E03693; E09206

HMDB: ID HMDB0011177

Metabolomics Workbench: ID 78930

Nikkaji: ID J661.079J

PubChem: CID 7020641

SureChEMBL: ID SCHEMBL3726264

ZINC: ID ZINC02392313