BIOPEP-UWM: Report

ID 8523
Name dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
sequence
VAGTWY
Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
6
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 695.7608 Monoisotopic mass 695.3268
EC50 :
174.00 µM


Bibliographic data:
Authors
Lacroix I. M. E., Li-Chan E. C. Y.
Title
Evaluation of the potential of dietary proteins as precursors of dipeptidyl peptidase (DPP)-IV inhibitors by an in silico approach. J. Funct. Foods, 4, 403-422, 2012
Year Source
2012 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@@](C)(NC(=O)[C@@]([H])(N)C(C)C)C(=O)NCC(=O)N[C@]([H])(C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(O)=O)[C@@]([H])(C)O

InChI=1S/C34H45N7O9/c1-17(2)28(35)32(47)38-18(3)30(45)37-16-27(44)41-29(19(4)42)33(48)39-25(14-21-15-36-24-8-6-5-7-23(21)24)31(46)40-26(34(49)50)13-20-9-11-22(43)12-10-20/h5-12,15,17-19,25-26,28-29,36,42-43H,13-14,16,35H2,1-4H3,(H,37,45)(H,38,47)(H,39,48)(H,40,46)(H,41,44)(H,49,50)/t18-,19+,25-,26-,28-,29-/m0/s1

InChIKey=UAXLUTAGJSXJNR-WVTHTGLTSA-N


Inhibitor of angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 3509)
Antibacterial peptide according to the BIOPEP-UWM database of bioactive peptides (ID 4014), the MBPDB database
Immunomodulating peptide according to the BIOPEP-UWM database of bioactive peptides (ID 8498); the MBPDB database
Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9435); the MBPDB database


Database reference:
AHTPDB: ID 1194, 1297, 2535, 5391, 5901, 6428

BioPepDB: ID biopep01328; biopep03964

BIOPEP-UWM database of bioactive peptides: ID 3509; 4014; 8498; 9435

EROP-Moscow: ID E07163

J-GLOBAL: ID 200907076795280258

MBPDB: Peptide VAGTWY

MilkAMP: ID BLA0002

Nikkaji: ID J1.595.467A

PubChem: CID 53311147

SATPdb: ID satpdb10794