BIOPEP-UWM: Report

ID 8555
Name dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
sequence
FL
Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
2
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 278.3459 Monoisotopic mass 278.1625
IC50 :
399.58 µM


Bibliographic data:
Authors
Nongonierma A. B., Mooney C., Shields D. C., FitzGerald R. J.
Title
Inhibition of dipeptidyl peptidase IV and xanthine oxidase by amino acids and dipeptides. Food Chemistry, 141, 644-653, 2013
Year Source
2013 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: CC(C)C[C@@H](C(=O)O)NC(=O)[C@H](Cc1ccccc1)N

InChI=1S/C15H22N2O3/c1-10(2)8-13(15(19)20)17-14(18)12(16)9-11-6-4-3-5-7-11/h3-7,10,12-13H,8-9,16H2,1-2H3,(H,17,18)(H,19,20)/t12-,13-/m0/s1

InChIKey: RFCVXVPWSPOMFJ-STQMWFEESA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BindingDB database; the BRENDA database; the EROP-Moscow database; the PubChem database
Inhibitor of Dipeptidyl Deptidase III (EC 3.4.14.4) (MEROPS ID: M49.001) according to the BIOPEP-UWM database of bioactive peptides (ID 9502); the BRENDA database
Inhibitor of pseudolysin (EC 3.4.24.26) (MEROPS ID: M04.005) according to the BRENDA database
Inhibitor of Aminopeptidase B (EC 3.4.11.6) (MEROPS ID: M01.014) according to the BindingDB database; the ChEMBL database
Inhibitor of Membrane alanyl aminopeptidase (EC 3.4.11.2) (MEROPS ID: M01.001 (another names: aminopeptidase M; aminopeptidase N) according to the BindingDB database; the ChEMBL database
Inhibitor of Neprilysin (EC 3.4.24.11) (MEROPS ID: M13.001) according to the BindingDB database; the ChEMBL database

Bitter peptide according to the BIOPEP database of sensory peptides and amino acids (ID 42); the BitterDB database; the ChEMBL database; the PubChem database


Database reference:
ACToR: ID 3303-55-7

AHTPDB: ID 1219; 1436; 1988; 3877; 5411; 5415

BindingDB: ID 50282727

BioPepDB: ID biopep00251

BIOPEP-UWM database of bioactive peptides: ID 9502

BIOPEP-UWM database of sensory peptides and amino acids: ID 42

BitterDB: ID 836

BRENDA: Ligand Phe-Leu

ChEMBL: ID CHEMBL37879

ChemIDplus: ID 3303-55-7

ChemSpider ID: 69264

CTD: ID 3303-55-7

EROP-Moscow: ID E01597

J-GLOBAL: ID 200907070370465370

MBPDB: Peptide FL

Metabolights: ID MTBLC91150

Nikkaji: ID J80.688I

PubChem: ID 76808

SATPdb: ID satpdb22674

SureChEMBL: ID SCHEMBL1396480

ZINC: ID ZINC000002390944