BIOPEP-UWM: Report

ID 8611
Name dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
sequence
WRP
Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
3
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 457.5248 Monoisotopic mass 457.2431
IC50 :
780.00 µM


Bibliographic data:
Authors
Lan V. T. T., Ito K., Ito S., Kawarasaki Y.
Title
Trp-Arg-Xaa tripeptides act as uncompetitive-type inhibitors of human dipeptidyl peptidase IV. Peptides, 54, 166-170, 2014
Year Source
2014 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N1[C@@]([H])(CCC1)C(=O)O

InChI=1S/C22H31N7O4/c23-15(11-13-12-27-16-6-2-1-5-14(13)16)19(30)28-17(7-3-9-26-22(24)25)20(31)29-10-4-8-18(29)21(32)33/h1-2,5-6,12,15,17-18,27H,3-4,7-11,23H2,(H,28,30)(H,32,33)(H4,24,25,26)/t15-,17-,18-/m0/s1

InChIKey=VIWQOOBRKCGSDK-SZMVWBNQSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides


Database reference:
BIOPEP-UWM database of bioactive peptides