BIOPEP-UWM: Report

ID 8615
Name dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
sequence
YPYY
Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
4
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 604.6488 Monoisotopic mass 604.2524
EC50 :
149.40 µM


Bibliographic data:
Authors
Nongonierma A. B., FitzGerald R. J.
Title
Susceptibility of milk protein-derived peptides to dipeptidyl peptidase IV (DPP-IV) hydrolysis. Food Chemistry 145, 845-852, 2014
Year Source
2014 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(Cc1ccc(O)cc1)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(O)=O

InChI=1S/C32H36N4O8/c33-25(16-19-3-9-22(37)10-4-19)31(42)36-15-1-2-28(36)30(41)34-26(17-20-5-11-23(38)12-6-20)29(40)35-27(32(43)44)18-21-7-13-24(39)14-8-21/h3-14,25-28,37-39H,1-2,15-18,33H2,(H,34,41)(H,35,40)(H,43,44)/t25-,26-,27-,28-/m0/s1

InChIKey=GINKSLAFZJESRI-LJWNLINESA-N


Opioid antagonist according to the BIOPEP-UWM database of bioactive peptides (ID 3218)
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 9724); the MBPDB database
Ileum contracting peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9725)


Database reference:
AHTPDB: ID 1014, 4173, 4885, 4989

BioPepDB: ID biopep01613

BIOPEP-UWM database of bioactive peptides: ID 3218; 9724; 9725

EROP-Moscow: ID E07424

J-GLOBAL: ID 200907040748245172

MBPDB: peptide YPYY

Nikkaji: ID J448.894F

PepBank: peptide YPYY

PubChem: CID 71352082

SATPdb: ID satpdb29145