BIOPEP-UWM: Report

ID 8621
Name dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
sequence
IPAVFK
Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
6
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 673.8410 Monoisotopic mass 673.4150
EC50 :
143.00 µM


Bibliographic data:
Authors
Silveira S. T., Martínez-Maqueda D., Recio I., Hernández-Ledesma B.
Title
Dipeptidyl peptidase-IV inhibitory peptides generated by tryptic hydrolysis of a whey protein concentrate rich in beta-lactoglobulin. Food Chemistry 141, 1072-1077, 2013
Year Source
2013 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: [H][C@@](C)(NC(=O)[C@]1([H])CCCN1C(=O)[C@@]([H])(N)[C@@H](C)CC)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CCCCN)C(O)=O

InChI=1S/C34H55N7O7/c1-6-21(4)27(36)33(46)41-18-12-16-26(41)31(44)37-22(5)29(42)40-28(20(2)3)32(45)39-25(19-23-13-8-7-9-14-23)30(43)38-24(34(47)48)15-10-11-17-35/h7-9,13-14,20-22,24-28H,6,10-12,15-19,35-36H2,1-5H3,(H,37,44)(H,38,43)(H,39,45)(H,40,42)(H,47,48)/t21-,22-,24-,25-,26-,27-,28-/m0/s1

InChIKey: XPBHUUFREVSIGR-OVELHQAISA-N


Antibacterial peptide according to the BIOPEP-UWM database of bioactive peptides (ID 8196), the EROP-Moscow database, the MBPDB database
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP database of bioactive peptides (ID 9232); the MBPDB database

Predicted ligand of SARS-CoV-2 parent protease (EC 3.4.22.69) (MEROPS ID: C30.007) (PDB: 6M03 and PDB: 6LU7) according to the BIOPEP-UWM Virtual database (ID 26)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 8196; 9232

BIOPEP-UWM Virtual database: ID 26

ChemSpider: ID 8524993

EROP-Moscow: ID E07165

J-GLOBAL: ID 200907037042020070

MBPDB: Peptide IPAVFK

Nikkaji: ID J1.595.466C

PubChem: CID 10349537