BIOPEP-UWM: Report

ID 8657
Name dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
sequence
LPQNIPP

Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
7
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 777.9056 Monoisotopic mass 777.4371
IC50 :
160.00 µM



Bibliographic data:
Authors
Uenishi H., Kabuki T., Seto Y., Serizawa A., Nakajima H.
Title
Isolation and identification of casein-derived dipeptidyl-peptidase 4 (DPP-4)-inhibitory peptide LPQNIPPL from gouda-type cheese and its effect on plasma glucose in rats. Int. Dairy J., 22, 24-30, 2012
Year Source
2012 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)O

InChI=1S/C36H59N9O10/c1-5-20(4)29(35(53)44-15-7-10-25(44)34(52)45-16-8-11-26(45)36(54)55)42-31(49)23(18-28(39)47)41-30(48)22(12-13-27(38)46)40-32(50)24-9-6-14-43(24)33(51)21(37)17-19(2)3/h19-26,29H,5-18,37H2,1-4H3,(H2,38,46)(H2,39,47)(H,40,50)(H,41,48)(H,42,49)(H,54,55)/t20-,21-,22-,23-,24-,25-,26-,29-/m0/s1

InChIKey=YBLYNIUUDBPIIG-FQQJYGDKSA-N



Database reference:
ChemSpider: ID 13164960

EPA DSSTox: ID DTXSID80581206

EROP-Moscow: ID E23835

FeptideDB: ID 8657

MBPDB: Peptide LPQNIPP

PubChem: CID 16036362