BIOPEP-UWM: Report

ID 8658
Name dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
sequence
VPITPT
Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
6
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 626.7401 Monoisotopic mass 626.3627
IC50 :
130.00 µM


Bibliographic data:
Authors
Uenishi H., Kabuki T., Seto Y., Serizawa A., Nakajima H.
Title
Isolation and identification of casein-derived dipeptidyl-peptidase 4 (DPP-4)-inhibitory peptide LPQNIPPL from gouda-type cheese and its effect on plasma glucose in rats. Int. Dairy J., 22, 24-30, 2012
Year Source
2012 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)O

InChI=1S/C29H50N6O9/c1-7-15(4)21(31-24(38)18-10-8-12-34(18)27(41)20(30)14(2)3)26(40)32-22(16(5)36)28(42)35-13-9-11-19(35)25(39)33-23(17(6)37)29(43)44/h14-23,36-37H,7-13,30H2,1-6H3,(H,31,38)(H,32,40)(H,33,39)(H,43,44)/t15-,16+,17+,18-,19-,20-,21-,22-,23-/m0/s1

InChIKey=SJZSLGPYAVBLSF-JRJRRAIFSA-N


Database reference:
ChemSpider: ID 13164845

EPA DSSTox: ID DTXSID10581198

EROP-Moscow: ID E23833

FeptideDB: ID 8658

MBPDB: Peptide VPITPT

PubChem: CID 16036247