BIOPEP-UWM: Report

ID 8675
Name dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
sequence
WR
Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
2
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 360.4099 Monoisotopic mass 360.1905
IC50 :
37.80 µM


Bibliographic data:
Authors
Nongonierma A. B., Mooney C., Shields D. C., FitzGerald R. J.
Title
In silico approaches to predict the potential of milk protein-derivedpeptides as dipeptidyl peptidase IV (DPP-IV) inhibitors. Peptides 57, 43-51, 2014
Year Source
2014 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

InChI=1S/C17H24N6O3/c18-12(8-10-9-22-13-5-2-1-4-11(10)13)15(24)23-14(16(25)26)6-3-7-21-17(19)20/h1-2,4-5,9,12,14,22H,3,6-8,18H2,(H,23,24)(H,25,26)(H4,19,20,21)/t12-,14-/m0/s1

InChIKey=LCPVBXOHXMBLFW-JSGCOSHPSA-N


Antagonist of Peroxisome proliferator-activated receptor γ (PPARγ) according to the BIOPEP-UWM database of biactive peptides; the ChEMBL database


Database reference:
BindingDB: ID 50266680

BMDB: ID BMDB62263

BRENDA: Ligand L-tryptophyl-L-arginine

ChEBI: ID 74866

ChEMBL: ID CHEMBL477417

EROP-Moscow: ID E10607

FooDB: ID FDB098229

HMDB: ID HMDB0029077

J-GLOBAL: ID 200907094178310172

Metabolights: ID MTBLC74866

Metabolomics Workbench: ID 78997

Nikkaji: ID J1.237.420H

PubChem: CID 25186251

SureChEMBL: ID SCHEMBL4947728

UniChem: ID 75466

Wikidata: ID Q27144975

ZINC: ID ZINC000002561117