BIOPEP-UWM: Report

ID 8677
Name dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
sequence
WL
Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
2
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 317.3819 Monoisotopic mass 317.1734
IC50 :
43.60 µM


Bibliographic data:
Authors
Nongonierma A. B., Mooney C., Shields D. C., FitzGerald R. J.
Title
In silico approaches to predict the potential of milk protein-derived peptides as dipeptidyl peptidase IV (DPP-IV) inhibitors. Peptides 57, 43-51, 2014
Year Source
2014 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: CC(C)C[C@H](NC(=O)[C@@H](N)CC1=CNC2=CC=CC=C12)C(O)=O

InChI=1S/C17H23N3O3/c1-10(2)7-15(17(22)23)20-16(21)13(18)8-11-9-19-14-6-4-3-5-12(11)14/h3-6,9-10,13,15,19H,7-8,18H2,1-2H3,(H,20,21)(H,22,23)/t13-,15-/m0/s1

InChIKey: LYMVXFSTACVOLP-ZFWWWQNUSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Inhibitor of Peroxisome proliferator-activated receptor gamma according to BindingDB database; ChEMBL database
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 9107)

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids; the BitterDB database


Database reference:
AHTPDB: ID 1463; 1900; 2968; 4724; 5181; 6216; 6220; 6862

BindingDB: ID 50266681

BIOPEP-UWM database of bioactive peptides: ID 8677

BIOPEP-UWM database of sensory peptides and amino acids: ID 338

BRENDA: Ligand Trp-Leu

BitterDB: ID 830

ChEBI: ID 74871

ChEMBL: ID CHEMBL477627

ChemSpider: ID 5365198

EROP-Moscow: ID E06385

J-GLOBAL: ID 200907089186452560

Nikkaji: ID J236.159K

PubChem: ID 6997509

SATPdb: ID satpdb20928

Therapeutic Target Database (TTD): ID DNC009657

ZINC: ID ZINC01865984