BIOPEP-UWM: Report

ID 8678
Name dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
sequence
WQ

Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
2
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 332.3536 Monoisotopic mass 332.1480
IC50 :
120.30 µM



Bibliographic data:
Authors
Nongonierma A. B., Mooney C., Shields D. C., FitzGerald R. J.
Title
In silico approaches to predict the potential of milk protein-derived peptides as dipeptidyl peptidase IV (DPP-IV) inhibitors. Peptides 57, 43-51, 2014
Year Source
2014 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)O

InChI=1S/C16H20N4O4/c17-11(7-9-8-19-12-4-2-1-3-10(9)12)15(22)20-13(16(23)24)5-6-14(18)21/h1-4,8,11,13,19H,5-7,17H2,(H2,18,21)(H,20,22)(H,23,24)/t11-,13-/m0/s1

InChIKey=NZCPCJCJZHKFGZ-AAEUAGOBSA-N


Antagonist of Peroxisome proliferator-activated receptor γ (PPARγ) according to the BIOPEP-UWM database of bioactive peptides; the ChEMBL database



Database reference:
AHTPDB: ID 1337, 4151, 4948

BindingDB: ID BDBM50266654

ChEBI: ID 157897

ChEMBL: ID CHEMBL476173

ChemSpider: ID 24697298

DSigDB: ID d4ttd_6061

EROP-Moscow: ID E10609

Metabolomics Workbench: ID 79001

PubChem: CID 25185698

SATPdb: ID satpdb18242

SureChEMBL: ID SCHEMBL5970454

ZINC: ID ZINC000040439750