BIOPEP-UWM: Report

ID 8747
Name Alpha-glucosidase inhibitor from egg yolk
sequence
YINQMPQKSRE
Function:
Inhibitor of alpha-glucosidase (EC 3.2.1.20)
 
Number of residues
11
Activity code
glui
Activity :
alpha-glucosidase inhibitor
Chemical mass 1393.5650 Monoisotopic mass 1392.6798
IC50 :
1215.42 µM


Bibliographic data:
Authors
Zambrowicz A., Pokora M., Setner B., Dąbrowska A., Szołtysik M., Babij K., Szewczuk Z., Trziszka T., Lubec G., Chrzanowska J.
Title
Multifunctional peptides derived from an egg yolk protein hydrolysate: isolation and characterization. Amino Acids 47, 369-380, 2015
Year Source
2015 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: [H][C@](N)(Cc1ccc(O)cc1)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CCSC)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CCC(O)=O)C(O)=O

InChI=1S/C59H96N18O19S/c1-4-30(2)47(76-48(85)33(61)27-31-12-14-32(79)15-13-31)56(93)74-40(28-45(64)82)53(90)70-36(16-19-43(62)80)52(89)72-38(22-26-97-3)57(94)77-25-8-11-42(77)55(92)71-37(17-20-44(63)81)51(88)68-34(9-5-6-23-60)50(87)75-41(29-78)54(91)69-35(10-7-24-67-59(65)66)49(86)73-39(58(95)96)18-21-46(83)84/h12-15,30,33-42,47,78-79H,4-11,16-29,60-61H2,1-3H3,(H2,62,80)(H2,63,81)(H2,64,82)(H,68,88)(H,69,91)(H,70,90)(H,71,92)(H,72,89)(H,73,86)(H,74,93)(H,75,87)(H,76,85)(H,83,84)(H,95,96)(H4,65,66,67)/t30-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,47-/m0/s1

InChIKey: WOGLIZJTFLKEIL-FQOONHDLSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 8742)
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8739)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 8739; 8742