BIOPEP-UWM: Report
ID | 8806 |
Name | dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) |
sequence |
Function: | |||
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) | |||
Number of residues | 2 |
Activity code | dpp |
Activity : | dipeptidyl peptidase IV inhibitor |
|||
Chemical mass | 287.3576 | Monoisotopic mass | 287.1952 | |
EC50 : | 0.00 µM |
Bibliographic data: | |
Authors | |
Lan V. T. T., Ito K., Ohno M., Motoyama T., Ito S., Kawarasaki Y. | |
Title | |
Analyzing a dipeptide library to identify human dipeptidyl peptidase IV inhibitor. Food Chemistry 175, 66-73 | |
Year | Source |
2015 | Journal |
Additional information: |
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)([C@@H](C)CC)C(=O)N[C@@]([H])(CCCNC(N)=N)C(O)=O InChI=1S/C12H25N5O3/c1-3-7(2)9(13)10(18)17-8(11(19)20)5-4-6-16-12(14)15/h7-9H,3-6,13H2,1-2H3,(H,17,18)(H,19,20)(H4,14,15,16)/t7-,8-,9-/m0/s1 InChIKey=HYXQKVOADYPQEA-CIUDSAMLSA-N Isolated from bovine beta-lactoglobulin hydrolysate FitzGerald R. J., Meisel H., 1999, Lactokinins: Whey protein-derived ACE inhibitory peptides. Nahrung 43, 165-167 Isolated from hen ovotransferrin hydrolysate Huang W.-Y., Majumder K., Wu J., 2010, Oxygen radical absorbance capacity of peptides from egg white protein ovotransferrin and their interactions with phytochemicals. Food Chem., 123, 635-641 Found in amaranth proteins: Barba de la Rosa A. P., Barba Montoya A., Martínez-Cuevas P., Hernández-Ledesma B., León-Galván M. F., De León-Rodríguez A., González C., 2010, Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: antihypertensive role of amaranth peptides. Nitric Oxide, 23, 106-111 Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; BIOPEP-UWM database of bioactive peptides (ID 3258); the EROP-Moscow database Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 8215) Inhibitor of Renin (EC 3.4.23.15) (MEROPS ID A01.007) according to the BIOPEP-UWM database of bioactive peptides (ID 8246) Inhibitor of calmodulin-dependent phosphodiesterase 1 (CaMPDE) (EC 3.1.4.17) according to the BIOPEP-UWM database of bioactive peptides (ID 8247) |
Database reference: |
AHTPDB: ID 1148, 1433, 1508, 3163, 3195, 3501, 3566, 3958, 4082, 5596, 5859 BioPepDB: ID biopep00580 BIOPEP-UWM database of bioactive peptides: ID 3258; 8215; 8246; 8247 BRENDA: Ligand Ile-Arg ChEBI: ID 74061 ChemSpider: ID 5384711 EROP-Moscow: ID E09248 MBPDB: peptide IR PubChem: CID 7021814 SATPdb: ID satpdb20125 |