BIOPEP-UWM: Report

ID 8880
Name dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
sequence
QW
Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
2
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 332.3536 Monoisotopic mass 332.1480
EC50 :
0.00 µM


Bibliographic data:
Authors
Lan V. T. T., Ito K., Ohno M., Motoyama T., Ito S., Kawarasaki Y.
Title
Analyzing a dipeptide library to identify human dipeptidyl peptidase IV inhibitor. Food Chemistry 175, 66-73
Year Source
2015 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCC(=O)N)C(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)O

InChI=1S/C16H20N4O4/c17-11(5-6-14(18)21)15(22)20-13(16(23)24)7-9-8-19-12-4-2-1-3-10(9)12/h1-4,8,11,13,19H,5-7,17H2,(H2,18,21)(H,20,22)(H,23,24)/t11-,13-/m0/s1

InChIKey=ZQFAGNFSIZZYBA-AAEUAGOBSA-N


Bioactivity predicted using molecular docking



Antioxidative peptide according to the EROP-Moscow database
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the EROP-Moscow database

Predicted ligand of SARS-CoV-2 parent protease (EC 3.4.22.69) (MEROPS ID: C30.007) (PDB ID: 6LU7) according to the BIOPEP-UWM Virtual database (ID 65)


Database reference:
BIOPEP-UWM Virtual database: ID 64

ChEBI: ID 141431

ChemSpider: ID 57558077

EPA CompTox: ID DTXSID30648959

EROP-Moscow: ID E10615

FeptideDB: ID 8880

FooDB: ID FDB111854

HMDB: ID HMDB0028808

J-GLOBAL: ID 201407058609422945

Nikkaji: ID J3.262.882F

PubChem: CID 25176542

SureChEMBL: ID SCHEMBL1898083