BIOPEP-UWM: Report

ID 9021
Name ACE inhibitor
sequence
TGLKP

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
5
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 514.6139 Monoisotopic mass 514.3105
IC50 :
51.57 µM



Bibliographic data:
Authors
Escudero E., Mora L., Toldrá F.
Title
Stability of ACE inhibitory ham peptides against heat treatment and in vitro digestion. Food Chemistry, 161, 305-311, 2014
Year Source
2014 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])([C@]([H])(O)C)C(=O)NCC(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N1[C@@]([H])(CCC1)C(=O)O

InChI=1S/C23H42N6O7/c1-13(2)11-16(27-18(31)12-26-21(33)19(25)14(3)30)20(32)28-15(7-4-5-9-24)22(34)29-10-6-8-17(29)23(35)36/h13-17,19,30H,4-12,24-25H2,1-3H3,(H,26,33)(H,27,31)(H,28,32)(H,35,36)/t14-,15+,16+,17+,19+/m1/s1

InChIKey=YPNYSIIXZWGZOP-QSUVVDIXSA-N


Peptide derived from Spanish dry-cured ham. ACE inhibitory activity expressed as IC50 = 51.57uM.



Database reference: