BIOPEP-UWM: Report

ID 9030
Name ACE inhibitor
sequence
RVY

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 436.5040 Monoisotopic mass 436.2427
EC50 :
205.60 µM



Bibliographic data:
Authors
Matsufuji H., Matsui T., Seki E., Osajima K., Nakashima M., Osajima Y.
Title
Angiotensin I-converting enzyme inhibitory peptides in an alkaline protease hydrolyzate derived from sardine muscle. Biosci. Biotech. Biochem., 58, 2244-2245, 1994
Year Source
1994 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O

InChI=1S/C20H32N6O5/c1-11(2)16(26-17(28)14(21)4-3-9-24-20(22)23)18(29)25-15(19(30)31)10-12-5-7-13(27)8-6-12/h5-8,11,14-16,27H,3-4,9-10,21H2,1-2H3,(H,25,29)(H,26,28)(H,30,31)(H4,22,23,24)/t14-,15-,16-/m0/s1

InChIKey=WHLDJYNHXOMGMU-JYJNAYRXSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001

Hypouricemic peptide according to the BIOPEP-UWM database of bioactive peptides


Antiviral peptide according to the BIOPEP-UWM Virtual database (ID 53)





Database reference:
AHTPDB: ID 1103, 1532, 4760, 5084, 5249, 6182

BioPepDB: ID biopep01229

BIOPEP-UWM Virtual database: ID 53

BRENDA: Ligand Arg-Val-Tyr

ChemSpider ID: 13164586

EPA DSSTox: ID DTXCID10531936

EROP-Moscow: ID E01341

PubChem: CID 16035988

SATPdb: ID satpdb24293