BIOPEP-UWM: Report

ID 9035
Name ACE inhibitor
sequence
GSH

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 299.2825 Monoisotopic mass 299.1226
IC50 :
32.36 µM



Bibliographic data:
Authors
Wu J., Aluko R. E., Nakai S.
Title
Structural requirements of angiotensin I-converting enzyme inhibitory activity: quantitative structure-activity relationship study of di- and tripeptides. J. Agric. Food Chem., 54, 732-738, 2006
Year Source
2006 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=C[N]([H])C=N1)C(=O)O

InChI=1S/C11H17N5O5/c12-2-9(18)15-8(4-17)10(19)16-7(11(20)21)1-6-3-13-5-14-6/h3,5,7-8,17H,1-2,4,12H2,(H,13,14)(H,15,18)(H,16,19)(H,20,21)/t7-,8-/m0/s1

InChIKey: MKIAPEZXQDILRR-YUMQZZPRSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001

Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9954); the EROP-Moscow database



Database reference:
AHTPDB: ID 1558

BioPepDB: ID biopep00415

BIOPEP-UWM database of bioactive peptides: ID 9954

EROP-Moscow: ID E23556

PubChem CID: 145455685

SATPdb: ID satpdb12942