BIOPEP-UWM: Report

ID 9048
Name ACE inhibitor
sequence
LVQ
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 358.4320 Monoisotopic mass 358.2209
IC50 :
14.13 µM


Bibliographic data:
Authors
Wu J., Aluko R. E., Nakai S.
Title
Structural requirements of angiotensin I-converting enzyme inhibitory activity: quantitative structure-activity relationship study of di- and tripeptides. J. Agric. Food Chem., 54, 732-738, 2006
Year Source
2006 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)O

InChI=1S/C16H30N4O5/c1-8(2)7-10(17)14(22)20-13(9(3)4)15(23)19-11(16(24)25)5-6-12(18)21/h8-11,13H,5-7,17H2,1-4H3,(H2,18,21)(H,19,23)(H,20,22)(H,24,25)/t10-,11-,13-/m0/s1

InChIKey: MVJRBCJCRYGCKV-GVXVVHGQSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Database reference:
AHTPDB: ID 1577

SATPdb: ID satpdb19047