BIOPEP-UWM: Report

ID 9051
Name ACE inhibitor
sequence
RPP

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 368.4302 Monoisotopic mass 368.2166
IC50 :
0.00 µM



Bibliographic data:
Authors
Wu J., Aluko R. E., Nakai S.
Title
Structural requirements of angiotensin I-converting enzyme inhibitory activity: quantitative structure-activity relationship study of di- and tripeptides. J. Agric. Food Chem., 54, 732-738, 2006
Year Source
2006 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCCNC(=N)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)O

InChI=1S/C16H28N6O4/c17-10(4-1-7-20-16(18)19)13(23)21-8-2-5-11(21)14(24)22-9-3-6-12(22)15(25)26/h10-12H,1-9,17H2,(H,25,26)(H4,18,19,20)/t10-,11-,12-/m0/s1

InChIKey: YCYXHLZRUSJITQ-SRVKXCTJSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Inhibitor of Neurolysin (EC 3.4.24.16) (MEROPS ID: M03.002) according to the BRENDA database



Database reference:
ACToR: ID 23815-91-0

AHTPDB: ID 1584

BioPepDB: ID biopep01218

BRENDA: Ligand Arg-Pro-Pro

ChemIDplus: ID 023815910

ChemSpider: ID 134551

CTD: ID 23815-91-0

J-GLOBAL: ID 200907087830984354

Nikkaji: ID J523.864A

PubChem: CID 152660

SATPdb: ID satpdb25900

SureChEMBL: ID SCHEMBL7272757

UniChem: Compound YCYXHLZRUSJITQ-SRVKXCTJSA-N

ZINC: ID ZINC000004899557