BIOPEP-UWM: Report

ID 9073
Name ACE inhibitor
sequence
TP
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 216.2337 Monoisotopic mass 216.1106
IC50 :
288.40 µM


Bibliographic data:
Authors
Wu J., Aluko R. E., Nakai S.
Title
Structural requirements of angiotensin I-converting enzyme inhibitory activity: quantitative structure-activity relationship study of di- and tripeptides. J. Agric. Food Chem., 54, 732-738, 2006
Year Source
2006 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@H](C(=O)N1[C@H](C(=O)O)CCC1)[C@H](O)C

InChI=1S/C9H16N2O4/c1-5(12)7(10)8(13)11-4-2-3-6(11)9(14)15/h5-7,12H,2-4,10H2,1H3,(H,14,15)/t5-,6+,7+/m1/s1

InChIKey: QOLYAJSZHIJCTO-VQVTYTSYSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database (ID 8503)

Sour peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 526)


Database reference:
AHTPDB: ID 1393, 1451, 4718, 5175, 5644, 6164

BindingDB: ID 50049714

BioPepDB: ID biopep01298

BIOPEP-UWM database of bioactive peptides: ID 8503

BIOPEP-UWM database of sensory peptides and amino acids: ID 526

BRENDA: Ligand Thr-Pro

ChEBI: ID 73662

ChEMBL: ID CHEMBL3321984

ChemSpider: ID 8010092

EPA CompTox: ID DTXSID40431470

J-GLOBAL: ID 200907063825682360

Metabolights: ID MTBLC73662

Nikkaji: ID J908.017A

PubChem: CID 9834371

SATPdb: ID satpdb27701

ZINC: ID ZINC000008076550