BIOPEP-UWM: Report

ID 9074
Name ACE inhibitor
sequence
DF
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 280.2759 Monoisotopic mass 280.1055
IC50 :
363.10 µM


Bibliographic data:
Authors
Wu J., Aluko R. E., Nakai S.
Title
Structural requirements of angiotensin I-converting enzyme inhibitory activity: quantitative structure-activity relationship study of di- and tripeptides. J. Agric. Food Chem., 54, 732-738, 2006
Year Source
2006 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)O

InChI=1S/C13H16N2O5/c14-9(7-11(16)17)12(18)15-10(13(19)20)6-8-4-2-1-3-5-8/h1-5,9-10H,6-7,14H2,(H,15,18)(H,16,17)(H,19,20)/t9-,10-/m0/s1

InChIKey: YZQCXOFQZKCETR-UWVGGRQHSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Inhibitor of Diaminopimelate dehydrogenase (EC 1.4.1.16) according to the BRENDA database
Inhibitor of Glutamate carboxypeptidase II (EC 3.4.17.21) according to the BRENDA database


Bitter peptide according to the ChEMBL database; the PubChem database


Database reference:
AHTPDB: ID 1396, 4710, 5140, 5647

BindingDB: ID 50049759

BioPepDB: ID biopep00124

BRENDA: Ligand Asp-Phe

ChEBI: ID 73830

ChEMBL: ID CHEMBL170376

ChemIDplus: ID 013433095

ChemSpider: ID 84028

HMDB: ID HMDB0000706

J-GLOBAL: ID 200907071476921290

Metabolights: ID MTBLC73830

Nikkaji: ID J27.535B

PubChem: CID 93078

SATPdb: ID satpdb10720