BIOPEP-UWM: Report

ID 9077
Name ACE inhibitor
sequence
YV
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 280.3188 Monoisotopic mass 280.1418
EC50 :
575.40 µM


Bibliographic data:
Authors
Wu J., Aluko R. E., Nakai S.
Title
Structural requirements of angiotensin I-converting enzyme inhibitory activity: quantitative structure-activity relationship study of di- and tripeptides. J. Agric. Food Chem., 54, 732-738, 2006
Year Source
2006 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(C(C)C)C(=O)O

InChI=1S/C14H20N2O4/c1-8(2)12(14(19)20)16-13(18)11(15)7-9-3-5-10(17)6-4-9/h3-6,8,11-12,17H,7,15H2,1-2H3,(H,16,18)(H,19,20)/t11-,12-/m0/s1

InChIKey: OYOQKMOWUDVWCR-RYUDHWBXSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Another reference concerning peptide:
Khueychai S., Jangpromma N., Choowongkomon K., Joompang A., Daduang S., Vesaratchavest M., Payoungkiattikun W., Tachibana S., Klaynongsruang S., A novel ACE inhibitory peptide derived from alkaline hydrolysis of ostrich (Struthio camelus) egg white ovalbumin. Process Biochem. 73, 235-245


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8946)


Database reference:
AHTPDB: ID 1416, 2688

BioPepDB: ID biopep01639

BIOPEP-UWM database of bioactive peptides: ID 8946

ChEBI: ID 75007

ChemSpider: ID 5373139

J-GLOBAL: ID 200907025118841649

Nikkaji: ID J149.636K

PubChem: CID 7009560

SATPdb: ID satpdb13043

SDBS: ID 4355