BIOPEP-UWM: Report

ID 9078
Name ACE inhibitor
sequence
YE
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 310.3018 Monoisotopic mass 310.1160
IC50 :
630.90 µM


Bibliographic data:
Authors
Wu J., Aluko R. E., Nakai S.
Title
Structural requirements of angiotensin I-converting enzyme inhibitory activity: quantitative structure-activity relationship study of di- and tripeptides. J. Agric. Food Chem., 54, 732-738, 2006
Year Source
2006 Journal


Additional information:

BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)O

InChI=1S/C14H18N2O6/c15-10(7-8-1-3-9(17)4-2-8)13(20)16-11(14(21)22)5-6-12(18)19/h1-4,10-11,17H,5-7,15H2,(H,16,20)(H,18,19)(H,21,22)/t10-,11-/m0/s1

InChIKey: PDSLRCZINIDLMU-QWRGUYRKSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8934)
Inhibitor of Glutamate carboxypeptidase (EC 3.4.17.11) (MEROPS ID: M20.001) according to the BRENDA database
Inhibitor of Glutamate carboxypeptidase II (EC 3.4.17.21) (MEROPS ID: M28.010) according to the BRENDA database
Inhibitor of Tubulin-tyrosine ligase (EC 6.3.2.25) according to the BRENDA database


Database reference:
AHTPDB: ID 1417

BioPepDB: ID biopep01551

BIOPEP-UWM database of bioactive peptides: ID 8934

BRENDA: Ligand Tyr-Glu

ChEBI: ID 74883

ChEMBL: ID CHEMBL1221519

ChemSpider: ID 5373208

J-GLOBAL: ID 200907003942622430

Metabolights: ID MTBLC74883

Nikkaji: ID J150.478I

PubChem: CID 7009628

SDBS: ID SDBS-9381

SureChEMBL: ID SCHEMBL1374181

ZINC: ID ZINC02384847