BIOPEP-UWM: Report

ID 9079
Name ACE inhibitor
sequence
IL
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 244.3296 Monoisotopic mass 244.1781
IC50 :
54.95 µM


Bibliographic data:
Authors
Wu J., Aluko R. E., Nakai S.
Title
Structural requirements of angiotensin I-converting enzyme inhibitory activity: quantitative structure-activity relationship study of di- and tripeptides. J. Agric. Food Chem., 54, 732-738, 2006
Year Source
2006 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@H](C(=O)N[C@H](C(=O)O)CC(C)C)[C@H](CC)C

InChI=1S/C12H24N2O3/c1-5-8(4)10(13)11(15)14-9(12(16)17)6-7(2)3/h7-10H,5-6,13H2,1-4H3,(H,14,15)(H,16,17)/t8-,9-,10-/m0/s1

InChIKey: JWBXCSQZLLIOCI-GUBZILKMSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8802)
Stimulator of glucose uptake according to the BIOPEP-UWM database of bioactive peptides (ID 8323); the EROP-Moscow database
Antinociceptive neuropeptide according to the ChEMBL database; the PubChem database
Inhibitor of citrulline uptake in yeasts according to the ChEMBL database; the PubChem database


Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids; the ChEMBL database


Database reference:
AHTPDB: ID 1438; 3860; 5410

BindingDB: ID 50282190

BioPepDB: ID biopep00542

BIOPEP-UWM database of bioactive peptides: ID 8323; 8802

BIOPEP database of sensory peptides and amino acids: ID 194

BRENDA: Ligand Ile-Ieu

ChEBI: ID 74072

ChEMBL: ID CHEMBL48832

ChemSpider: ID 5382050

EPA CompTox: ID DTXSID00427071

EPA DSSTox: ID DTXCID40377905

EROP-Moscow: ID E10605

J-GLOBAL: ID 200907038945135805

Metabolights: ID MTBLC74072

Nikkaji: ID J1.013.425K

PubChem: ID 7019083

SATPdb: ID satpdb25152

SureChEMBL: ID SCHEMBL3010040

ZINC: ID ZINC02556613