BIOPEP-UWM: Report

ID 9097
Name ACE inhibitor
sequence
GLTSK
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
5
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 504.5761 Monoisotopic mass 504.2898
EC50 :
65.40 µM


Bibliographic data:
Authors
Luna-Vital D. A., Gonzalez de Mejia E., Mendoza S., Loarca-Pina G.
Title
Peptides present in the non-digestible fraction of common beans (Phaseolus vulgaris L.) inhibit the angiotensin-I converting enzyme by interacting with its catalytic cavity independent of their antioxidant capacity. Food Funct., 6, 1470-1479, 2015
Year Source
2015 Journal


Additional information:

BIOPEP database of bioactive peptides


SMILES: NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)O

InChI=1S/C21H40N6O8/c1-11(2)8-14(24-16(30)9-23)18(31)27-17(12(3)29)20(33)26-15(10-28)19(32)25-13(21(34)35)6-4-5-7-22/h11-15,17,28-29H,4-10,22-23H2,1-3H3,(H,24,30)(H,25,32)(H,26,33)(H,27,31)(H,34,35)/t12-,13+,14+,15+,17+/m1/s1

InChIKey: NURUXHWYSWXTSX-MDLJMBGESA-N

Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9098)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9098