BIOPEP-UWM: Report

ID 9099
Name ACE inhibitor
sequence
MTEEY
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001)
 
Number of residues
5
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 671.7159 Monoisotopic mass 671.2462
EC50 :
90.30 µM


Bibliographic data:
Authors
Luna-Vital D. A., Gonzalez de Mejia E., Mendoza S., Loarca-Pina G.
Title
Peptides present in the non-digestible fraction of common beans (Phaseolus vulgaris L.) inhibit the angiotensin-I converting enzyme by interacting with its catalytic cavity independent of their antioxidant capacity. Food Funct., 6, 1470-1479, 2015
Year Source
2015 Journal


Additional information:

BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(C(O)C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)O

InChI=1S/C28H41N5O12S/c1-14(34)23(33-24(40)17(29)11-12-46-2)27(43)31-19(8-10-22(38)39)25(41)30-18(7-9-21(36)37)26(42)32-20(28(44)45)13-15-3-5-16(35)6-4-15/h3-6,14,17-20,23,34-35H,7-13,29H2,1-2H3,(H,30,41)(H,31,43)(H,32,42)(H,33,40)(H,36,37)(H,38,39)(H,44,45)/t14?,17-,18-,19-,20-,23-/m0/s1

InChIKey: AQODTKFHGCQVPE-JWVZIVEMSA-N

Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9100)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9100