BIOPEP-UWM: Report

ID 9101
Name ACE inhibitor
sequence
LSNGK
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
5
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 517.5749 Monoisotopic mass 517.2851
IC50 :
130.60 µM


Bibliographic data:
Authors
Luna-Vital D. A., Gonzalez de Mejia E., Mendoza S., Loarca-Pina G.
Title
Peptides present in the non-digestible fraction of common beans (Phaseolus vulgaris L.) inhibit the angiotensin-I converting enzyme by interacting with its catalytic cavity independent of their antioxidant capacity. Food Funct., 6, 1470-1479, 2015
Year Source
2015 Journal


Additional information:

BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(=O)N)C(=O)NCC(=O)N[C@@]([H])(CCCCN)C(=O)O

InChI=1S/C21H39N7O8/c1-11(2)7-12(23)18(32)28-15(10-29)20(34)27-14(8-16(24)30)19(33)25-9-17(31)26-13(21(35)36)5-3-4-6-22/h11-15,29H,3-10,22-23H2,1-2H3,(H2,24,30)(H,25,33)(H,26,31)(H,27,34)(H,28,32)(H,35,36)/t12-,13-,14-,15-/m0/s1

InChIKey: JHQFEFOCJCVJCJ-AJNGGQMLSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9102)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9102