BIOPEP-UWM: Report

ID 9103
Name ACE inhibitor
sequence
GEGSGA
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
6
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 476.4373 Monoisotopic mass 476.1860
IC50 :
113.70 µM


Bibliographic data:
Authors
Luna-Vital D. A., Gonzalez de Mejia E., Mendoza S., Loarca-Pina G.
Title
Peptides present in the non-digestible fraction of common beans (Phaseolus vulgaris L.) inhibit the angiotensin-I converting enzyme by interacting with its catalytic cavity independent of their antioxidant capacity. Food Funct., 6, 1470-1479, 2015
Year Source
2015 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N[C@@]([H])(CCC(=O)O)C(=O)NCC(=O)N[C@@]([H])(CO)C(=O)NCC(=O)N[C@@]([H])(C)C(=O)O

InChI=1S/C17H28N6O10/c1-8(17(32)33)21-12(26)5-20-16(31)10(7-24)23-13(27)6-19-15(30)9(2-3-14(28)29)22-11(25)4-18/h8-10,24H,2-7,18H2,1H3,(H,19,30)(H,20,31)(H,21,26)(H,22,25)(H,23,27)(H,28,29)(H,32,33)/t8-,9-,10-/m0/s1

InChIKey: UVITXXKRQQSNPB-GUBZILKMSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9104)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9104