BIOPEP-UWM: Report

ID 9110
Name ACE inhibitor
sequence
LNNSRAP
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
7
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 770.8321 Monoisotopic mass 770.4023
IC50 :
105.30 µM


Bibliographic data:
Authors
Ruiz-Giménez P., Salom J. B., Marcos J. F., Valles S., Martinez-Maqueda D., Recio I., Torregrosa G., Alborch E., Manzanares P.
Title
Antihypertensive effect of a bovine lactoferrin pepsin hydrolysate: Identification of novel active peptides. Food Chem., 131, 266-273, 2012
Year Source
2012 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)O

InChI=1S/C31H54N12O11/c1-14(2)10-16(32)24(47)40-18(11-22(33)45)26(49)41-19(12-23(34)46)27(50)42-20(13-44)28(51)39-17(6-4-8-37-31(35)36)25(48)38-15(3)29(52)43-9-5-7-21(43)30(53)54/h14-21,44H,4-13,32H2,1-3H3,(H2,33,45)(H2,34,46)(H,38,48)(H,39,51)(H,40,47)(H,41,49)(H,42,50)(H,53,54)(H4,35,36,37)/t15-,16-,17-,18-,19-,20-,21-/m0/s1

InChIKey: WYPUBMUVBADNFB-BPSSIEEOSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Database reference:
AHTPDB: ID 4333, 5524

BioPepDB: ID biopep00836

MBPDB: peptide LNNSRAP

SATPdb: ID satpdb10704