BIOPEP-UWM: Report

ID 9111
Name ACE inhibitor
sequence
DKVGINY
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
7
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 807.8886 Monoisotopic mass 807.4113
IC50 :
84.20 µM


Bibliographic data:
Authors
Tavares T., del Mar Contreras M., Amorim M., Pintado M., Recio I., Malcata F. X.
Title
Novel whey-derived peptides with inhibitory effect against angiotensin-converting enzyme: in vitro effect and stability to gastrointestinal enzymes. Peptides, 32, 1013-1019, 2011
Year Source
2011 Journal


Additional information:

BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

InChI=1S/C36H57N9O12/c1-5-19(4)30(35(55)42-24(16-26(39)47)33(53)43-25(36(56)57)14-20-9-11-21(46)12-10-20)44-27(48)17-40-34(54)29(18(2)3)45-32(52)23(8-6-7-13-37)41-31(51)22(38)15-28(49)50/h9-12,18-19,22-25,29-30,46H,5-8,13-17,37-38H2,1-4H3,(H2,39,47)(H,40,54)(H,41,51)(H,42,55)(H,43,53)(H,44,48)(H,45,52)(H,49,50)(H,56,57)/t19-,22-,23-,24-,25-,29-,30-/m0/s1

InChIKey: ZVESKUBHZIBSKD-QNUQHRJKSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Database reference:
AHTPDB: ID 1302, 2551

BioPepDB: ID biopep00138

MBPDB: Peptide DKVGINY

SATPdb: ID satpdb20790