BIOPEP-UWM: Report

ID 9113
Name ACE inhibitor
sequence
KGYGGVSL
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
8
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 779.8785 Monoisotopic mass 779.4164
IC50 :
253.60 µM


Bibliographic data:
Authors
Tavares T., del Mar Contreras M., Amorim M., Pintado M., Recio I., Malcata F. X.
Title
Novel whey-derived peptides with inhibitory effect against angiotensin-converting enzyme: in vitro effect and stability to gastrointestinal enzymes. Peptides, 32, 1013-1019, 2011
Year Source
2011 Journal


Additional information:

BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCCCN)C(=O)NCC(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)NCC(=O)NCC(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(C)C)C(=O)O

InChI=1S/C35H57N9O11/c1-19(2)13-25(35(54)55)42-33(52)26(18-45)43-34(53)30(20(3)4)44-29(49)16-38-27(47)15-40-32(51)24(14-21-8-10-22(46)11-9-21)41-28(48)17-39-31(50)23(37)7-5-6-12-36/h8-11,19-20,23-26,30,45-46H,5-7,12-18,36-37H2,1-4H3,(H,38,47)(H,39,50)(H,40,51)(H,41,48)(H,42,52)(H,43,53)(H,44,49)(H,54,55)/t23-,24-,25-,26-,30-/m0/s1

InChIKey: SWMAXAAOPLGWOO-WZFWIWBTSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Database reference:
AHTPDB: ID 2555

BioPepDB: ID biopep00676

MBPDB: Peptide KGYGGVSL

SATPdb: ID satpdb22869