BIOPEP-UWM: Report

ID 9125
Name ACE inhibitor
sequence
FEGTVFENG

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
9
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 999.0287 Monoisotopic mass 998.4330
IC50 :
0.00 µM



Bibliographic data:
Authors
Aluko R. E., Girgih A. T., He R., Malomo S., Li H., Offengenden M., Wu J.
Title
Structural and functional characterization of yellow field pea seed (Pisum sativum L.) protein-derived antihypertensive peptides. Food Res. Int., 77, 10-16, 2015
Year Source
2015 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)NCC(=O)N[C@@]([H])(C(O)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CC(=O)N)C(=O)NCC(=O)O

InChI=1S/C45H62N10O16/c1-23(2)37(55-45(71)38(24(3)56)54-33(58)21-48-40(66)28(14-16-34(59)60)50-39(65)27(46)18-25-10-6-4-7-11-25)44(70)53-30(19-26-12-8-5-9-13-26)43(69)51-29(15-17-35(61)62)42(68)52-31(20-32(47)57)41(67)49-22-36(63)64/h4-13,23-24,27-31,37-38,56H,14-22,46H2,1-3H3,(H2,47,57)(H,48,66)(H,49,67)(H,50,65)(H,51,69)(H,52,68)(H,53,70)(H,54,58)(H,55,71)(H,59,60)(H,61,62)(H,63,64)/t24?,27-,28-,29-,30-,31-,37-,38-/m0/s1

InChIKey: SPHVXKUUYHOXIF-CQWPEXIESA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Inhibitor of Renin (EC 3.4.23.15) (MEROPS ID A01.007) according to the BIOPEP-UWM database of bioactive peptides (ID (9126)



Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9126