BIOPEP-UWM: Report

ID 9126
Name Renin inhibitor
sequence
FEGTVFENG
Function:
Inhibitor of Renin (EC 3.4.23.15) (MEROPS ID A01.007)
 
Number of residues
9
Activity code
ren
Activity :
renin inhibitor
Chemical mass 999.0287 Monoisotopic mass 998.4330
EC50 :
0.00 µM


Bibliographic data:
Authors
Aluko R. E., Girgih A. T., He R., Malomo S., Li H., Offengenden M., Wu J.
Title
Structural and functional characterization of yellow field pea seed (Pisum sativum L.) protein-derived antihypertensive peptides. Food Res. Int., 77, 10-16, 2015
Year Source
2015 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](C)(O)[C@]([H])(NC(=O)CNC(=O)[C@]([H])(CCC(O)=O)NC(=O)[C@@]([H])(N)Cc1ccccc1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CC(N)=O)C(=O)NCC(O)=O

InChI=1S/C45H62N10O16/c1-23(2)37(55-45(71)38(24(3)56)54-33(58)21-48-40(66)28(14-16-34(59)60)50-39(65)27(46)18-25-10-6-4-7-11-25)44(70)53-30(19-26-12-8-5-9-13-26)43(69)51-29(15-17-35(61)62)42(68)52-31(20-32(47)57)41(67)49-22-36(63)64/h4-13,23-24,27-31,37-38,56H,14-22,46H2,1-3H3,(H2,47,57)(H,48,66)(H,49,67)(H,50,65)(H,51,69)(H,52,68)(H,53,70)(H,54,58)(H,55,71)(H,59,60)(H,61,62)(H,63,64)/t24-,27+,28+,29+,30+,31+,37+,38+/m1/s1

InChIKey=SPHVXKUUYHOXIF-XDZWWCOPSA-N



Information concerning Renin is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: A01.007


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 9125)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9125