BIOPEP-UWM: Report

ID 9130
Name Antioxidative peptide
sequence
VAWRNRCKGTD
Function:
Antioxidative peptide derived from hen egg white lysozyme (fragment 109-119).
 
Number of residues
11
Activity code
ao
Activity :
antioxidative
Chemical mass 1305.4635 Monoisotopic mass 1304.6389
EC50 :
0.00 µM


Bibliographic data:
Authors
Carrillo, W., Gómez-Ruiz, J. A., Miralles, B., Ramos, M., Barrio, D., Recio, I.
Title
Identification of antioxidant peptides of hen egg-white lysozyme and evaluation of inhibition of lipid peroxidation and cytotoxicity in the Zebrafish model. Eur. Food Res. Technol., 2016, 242(10), 1777-1785.
Year Source
2016 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c2ccccc2[nH]c1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)O

InChI=1S/C54H88N20O16S/c1-25(2)41(57)50(87)66-26(3)43(80)70-34(19-28-22-64-30-12-6-5-11-29(28)30)47(84)68-32(14-9-17-62-53(58)59)45(82)71-35(20-38(56)76)48(85)69-33(15-10-18-63-54(60)61)46(83)73-37(24-91)49(86)67-31(13-7-8-16-55)44(81)65-23-39(77)74-42(27(4)75)51(88)72-36(52(89)90)21-40(78)79/h5-6,11-12,22,25-27,31-37,41-42,64,75,91H,7-10,13-21,23-24,55,57H2,1-4H3,(H2,56,76)(H,65,81)(H,66,87)(H,67,86)(H,68,84)(H,69,85)(H,70,80)(H,71,82)(H,72,88)(H,73,83)(H,74,77)(H,78,79)(H,89,90)(H4,58,59,62)(H4,60,61,63)/t26-,27+,31-,32-,33-,34-,35-,36-,37-,41-,42-/m0/s1

InChIKey: XXFANRLHWVAQCM-IEQQXJPASA-N


Antioxidant activity (ORAC-FL test) was 1970 uM Trolox/uM peptide. Synthetic peptide inhibited lipid peroxidation in 36.8%.

Cytotoxic peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9135)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9135