BIOPEP-UWM: Report

ID 9131
Name Antioxidative peptide
sequence
WRNRCKGTD
Function:
Antioxidative peptide derived from hen egg white lysozyme (fragment 111-119).
 
Number of residues
9
Activity code
ao
Activity :
antioxidative
Chemical mass 1135.2551 Monoisotopic mass 1134.5337
EC50 :
0.00 µM


Bibliographic data:
Authors
Carrillo, W., Gómez-Ruiz, J. A., Miralles, B., Ramos, M., Barrio, D., Recio, I.
Title
Identification of antioxidant peptides of hen egg-white lysozyme and evaluation of inhibition of lipid peroxidation and cytotoxicity in the Zebrafish model. Eur. Food Res. Technol., 2016, 242(10), 1777-1785.
Year Source
2016 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](Cc1c2ccccc2[nH]c1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)O

InChI=1S/C46H74N18O14S/c1-22(65)36(43(76)62-31(44(77)78)18-35(68)69)64-34(67)20-57-38(71)27(10-4-5-13-47)59-42(75)32(21-79)63-40(73)29(12-7-15-55-46(52)53)60-41(74)30(17-33(49)66)61-39(72)28(11-6-14-54-45(50)51)58-37(70)25(48)16-23-19-56-26-9-3-2-8-24(23)26/h2-3,8-9,19,22,25,27-32,36,56,65,79H,4-7,10-18,20-21,47-48H2,1H3,(H2,49,66)(H,57,71)(H,58,70)(H,59,75)(H,60,74)(H,61,72)(H,62,76)(H,63,73)(H,64,67)(H,68,69)(H,77,78)(H4,50,51,54)(H4,52,53,55)/t22-,25+,27+,28+,29+,30+,31+,32+,36+/m1/s1

InChIKey: IVNLPCFFAAQPOC-LGTWEDLPSA-N


Antioxidant activity (ORAC-FL test) was 3123 uM Trolox/uM peptide. Synthetic peptide inhibited lipid peroxidation in 51.6%.

Cytotoxic peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9136)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9136