BIOPEP-UWM: Report

ID 9132
Name Antioxidative peptide
sequence
AWIRGCRL
Function:
Antioxidative peptide derived from hen egg white lysozyme (fragment 122-129).
 
Number of residues
8
Activity code
ao
Activity :
antioxidative
Chemical mass 974.1822 Monoisotopic mass 973.5265
EC50 :
0.00 µM


Bibliographic data:
Authors
Carrillo, W., Gómez-Ruiz, J. A., Miralles, B., Ramos, M., Barrio, D., Recio, I.
Title
Identification of antioxidant peptides of hen egg-white lysozyme and evaluation of inhibition of lipid peroxidation and cytotoxicity in the Zebrafish model. Eur. Food Res. Technol., 2016, 242(10), 1777-1785.
Year Source
2016 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](C)C(=O)N[C@@H](Cc1c2ccccc2[nH]c1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)O

InChI=1S/C43H71N15O9S/c1-6-23(4)34(58-38(63)30(56-35(60)24(5)44)18-25-19-51-27-12-8-7-11-26(25)27)40(65)55-28(13-9-15-49-42(45)46)36(61)52-20-33(59)53-32(21-68)39(64)54-29(14-10-16-50-43(47)48)37(62)57-31(41(66)67)17-22(2)3/h7-8,11-12,19,22-24,28-32,34,51,68H,6,9-10,13-18,20-21,44H2,1-5H3,(H,52,61)(H,53,59)(H,54,64)(H,55,65)(H,56,60)(H,57,62)(H,58,63)(H,66,67)(H4,45,46,49)(H4,47,48,50)/t23-,24-,28-,29-,30-,31-,32-,34-/m0/s1

InChIKey: JMRRCVTYFJUJSE-XBIGFWICSA-N


Antioxidant activity (ORAC-FL test) was 2743 uM Trolox/uM peptide. Synthetic peptide inhibited lipid peroxidation in 55.56%.

Cytotoxic peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9137)


Database reference:
BIOPEP-UWM database of biocative peptides: ID 9137