BIOPEP-UWM: Report

ID 9133
Name Antioxidative peptide
sequence
WIRGCRL
Function:
Antioxidative peptide derived from hen egg white lysozyme (fragment 123-129).
 
Number of residues
7
Activity code
ao
Activity :
antioxidative
Chemical mass 903.1045 Monoisotopic mass 902.4895
EC50 :
0.00 µM


Bibliographic data:
Authors
Carrillo, W., Gómez-Ruiz, J. A., Miralles, B., Ramos, M., Barrio, D., Recio, I.
Title
Identification of antioxidant peptides of hen egg-white lysozyme and evaluation of inhibition of lipid peroxidation and cytotoxicity in the Zebrafish model. Eur. Food Res. Technol., 2016, 242(10), 1777-1785.
Year Source
2016 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](Cc1c2ccccc2[nH]c1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)O

InChI=1S/C40H66N14O8S/c1-5-22(4)32(54-33(56)25(41)17-23-18-48-26-11-7-6-10-24(23)26)37(60)52-27(12-8-14-46-39(42)43)34(57)49-19-31(55)50-30(20-63)36(59)51-28(13-9-15-47-40(44)45)35(58)53-29(38(61)62)16-21(2)3/h6-7,10-11,18,21-22,25,27-30,32,48,63H,5,8-9,12-17,19-20,41H2,1-4H3,(H,49,57)(H,50,55)(H,51,59)(H,52,60)(H,53,58)(H,54,56)(H,61,62)(H4,42,43,46)(H4,44,45,47)/t22-,25-,27-,28-,29-,30-,32-/m0/s1

InChIKey: ZPLLFKWFGUIMHG-MYTRGFQGSA-N


Antioxidant activity (ORAC-FL test) was 2393 uM Trolox/uM peptide. Synthetic peptide inhibited lipid peroxidation in 63.2%.

Cytotoxic peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9138)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9138