BIOPEP-UWM: Report

ID 9134
Name Antioxidative peptide
sequence
IRGCRL
Function:
Antioxidative peptide derived from hen egg white lysozyme (fragment 124-129).
 
Number of residues
6
Activity code
ao
Activity :
antioxidative
Chemical mass 716.8950 Monoisotopic mass 716.4104
EC50 :
0.00 µM


Bibliographic data:
Authors
Carrillo, W., Gómez-Ruiz, J. A., Miralles, B., Ramos, M., Barrio, D., Recio, I.
Title
Identification of antioxidant peptides of hen egg-white lysozyme and evaluation of inhibition of lipid peroxidation and cytotoxicity in the Zebrafish model. Eur. Food Res. Technol., 2016, 242(10), 1777-1785.
Year Source
2016 Journal


Additional information:

BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)O

InChI=1S/C29H56N12O7S/c1-5-16(4)22(30)26(46)40-17(8-6-10-35-28(31)32)23(43)37-13-21(42)38-20(14-49)25(45)39-18(9-7-11-36-29(33)34)24(44)41-19(27(47)48)12-15(2)3/h15-20,22,49H,5-14,30H2,1-4H3,(H,37,43)(H,38,42)(H,39,45)(H,40,46)(H,41,44)(H,47,48)(H4,31,32,35)(H4,33,34,36)/t16-,17-,18-,19-,20-,22-/m0/s1

InChIKey: HXSGXIUYGKLXTE-HVYFOGIKSA-N


Antioxidant activity (ORAC-FL test) was 0.313 uM Trolox/uM peptide. Synthetic peptide inhibited lipid peroxidation in 61.0%.
Cytotoxic peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9139)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9139