BIOPEP-UWM: Report

ID 9140
Name ACE inhibitor
sequence
VDSDVVKG

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
8
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 817.8818 Monoisotopic mass 817.4167
IC50 :
13.30 µM



Bibliographic data:
Authors
Priyanto A. D., Doerksen R. J., Chang C.-I., Sung W.-C., Widjanarko S. B., Kusnadi J., Lin Y.-C., Wang T.-C., Hsu J.-L.
Title
Screening, discovery, and characterization of angiotensin-I converting enzyme inhibitory peptides derived from proteolytic hydrolysate of bitter melon seed proteins. J. Proteom., 128, 424-435, 2015
Year Source
2015 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)NCC(=O)O

InChI=1S/C34H59N9O14/c1-15(2)25(36)32(55)40-19(11-22(45)46)29(52)41-21(14-44)31(54)39-20(12-23(47)48)30(53)42-27(17(5)6)34(57)43-26(16(3)4)33(56)38-18(9-7-8-10-35)28(51)37-13-24(49)50/h15-21,25-27,44H,7-14,35-36H2,1-6H3,(H,37,51)(H,38,56)(H,39,54)(H,40,55)(H,41,52)(H,42,53)(H,43,57)(H,45,46)(H,47,48)(H,49,50)/t18-,19-,20-,21-,25-,26-,27-/m0/s1

InChIKey: SSNZSBXYWIAMCP-VQUVYUSASA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001



Database reference: