BIOPEP-UWM: Report

ID 9172
Name ACE inhibitor
sequence
PPP

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 309.3599 Monoisotopic mass 309.1683
IC50 :
78.20 µM



Bibliographic data:
Authors
Wu J., Aluko R. E.
Title
Quantitative structure-activity relationship study of bitter di- and tri-peptides including relationship with angiotensin I-converting enzyme inhibitory activity. J. Peptide Sci., 13, 63-69, 2007
Year Source
2007 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: C1C[C@@H](C(=O)N2CCC[C@H]2C(=O)N2CCC[C@H]2C(=O)O)NC1

InChI=1S/C15H23N3O4/c19-13(10-4-1-7-16-10)17-8-2-5-11(17)14(20)18-9-3-6-12(18)15(21)22/h10-12,16H,1-9H2,(H,21,22)/t10-,11-,12-/m0/s1

InChIKey: SBVPYBFMIGDIDX-SRVKXCTJSA-N


Inhibitor of Renin (EC 3.4.23.15) (MEROPS ID: A01.007) according to the PubChem database

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 6)



Database reference:
AHTPDB: ID 4572; 4848; 5486

BioPepDB: ID biopep01082

BIOPEP-UWM database of sensory peptides and amino acids: ID 6

ChEBI: ID 73647

ChemSpider: ID 388670

KEGG: ID C01843

PubChem: CID 439587

SATPdb: ID satpdb11296

ZINC: ID ZINC04095727